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James Provenzale, M.D.

Photo of James Provenzale

Phone: 919-684-7218

Physical Address:
1533 Hosp North
Durham, NC 27710

Postal Address:
Box 3808 Med Ctr
Durham, NC 27710

Email: prove001 AT mc DOT duke DOT edu

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Professor

Fitzpatrick Institute for Photonics

Radiology, Divison of Neuroradiology, School of Medicine

DIBS Faculty, Member, DIBS Chairs & Directors Advisory Council

Research Description

By training, I am a neurologist and a neuroradiologist. Much of my research has been in applications of diffusion tensor imaging to understand brain development in children as well as to elucidate disease mechanisms in adult and pediatric white matter diseases. In the past few years, my research has focused on applications of nanotechnology to oncology as well as to brain disorders. I am interested in developing nanotechnological techniques for imaging of CNS disorders, delivering therapy and re-engineering CNS tissue.

Education

Fellowship, Massachusetts General Hospital, Neuroradiology, 1990-1992

Residency, Massachusetts General Hospital, Radiology, 1987-1991

Residency, University of North Carolina, Neurology, 1984-1997

M.D., Albany Medical College, New York, 1983

M.A., Saint Louis University, 1978

B.A., Saint Louis University, 1976

Recent Publications

Mohs AM, Provenzale JM. Applications of nanotechnology to imaging and therapy of brain tumors. Neuroimaging Clin N Am. 2010 Aug;20(3):283-92.

Provenzale JM, Isaacson J, Chen S, Stinnett S, Liu C. Correlation of apparent diffusion coefficient and fractional anisotropy values in the developing infant brain. AJR Am J Roentgenol. 2010 Dec;195(6):W456-62.

Madden DJ, Spaniol J, Costello MC, Bucur B, White LE, Cabeza R, Davis SW, Dennis NA, Provenzale JM, Huettel SA. Cerebral white matter integrity mediates adult age differences in cognitive performance. J Cogn Neurosci. 2009 Feb;21(2):289-302.

Research Areas

Research Topics

  • Nanotechnology
  • Tumors
  • Brain development